BXD DOD Gulf War Illness

The study treated BXD male and female mice with 20mg% corticosterone in drinking water for 7 days. On the 8th day they were injected i.p. with 4mg/kg diisopropylflurophosphate, an irreversible cholinesterase inhibitor. Six hours after injection the prefrontal cortex was harvested to analyze gene expression for Il1b, Tnfa, Il6 by rtPCR.

D=diisopropylflurophosphate treatment

CD= corticosterone + diisopropylflurophosphate treatment.

Data are log2 gene expression for D or CD vs saline control

Group: DOD-BXD-GWI